Full metadata record
DC FieldValueLanguage
dc.contributor.author孫家偉en_US
dc.contributor.authorSun Chia-Weien_US
dc.date.accessioned2014-12-13T10:40:18Z-
dc.date.available2014-12-13T10:40:18Z-
dc.date.issued2014en_US
dc.identifier.govdocNSC101-2628-E009-026-MY3zh_TW
dc.identifier.urihttp://hdl.handle.net/11536/97383-
dc.identifier.urihttps://www.grb.gov.tw/search/planDetail?id=8124368&docId=433315en_US
dc.description.abstract本計畫目標在於開發時域式近紅外光擴散光學造影技術,用以針對精神及神經疾 病之大腦結構性及功能性影像量測。基於以往的研究成果,我們已於國際間首次 提出利用近紅外光進行大腦體積造影,並且於三維時域蒙地卡羅模擬中驗證該法 在阿茲海默患者診斷之可能性。同時,系統也將提供功能性腦造影,並且藉由多 種統計測試法找出影像特徵,在初步研究成果中,我們已利用雙樣本K﹣S 測試 法成功找出精神分裂症患者之前額葉區在接受VFT 刺激時含氧血紅素活化之光 拓撲影像的六個特徵通道,並將藉此分析提升臨床診斷之正確性。本計畫將沿續 以往研究成果,開發臨床用時域多點式擴散光學造影系統,針對大腦疾病進行結 構性及功能腦造影,期能在未來提供失智症/精神分裂症之殘障鑑定分級評估之 有效工具。zh_TW
dc.description.abstractThe goal of proposal is to develop a time-domain near-infrared diffuse optical imaging system for Alzheimer’s disease and schizophrenia evaluation with structural/functional imaging. Based on our previous results, we proposed a novel brain volumetric imaging (BVI) technique by using 3-D Monte Carlo simulation for feasibility validation. The results shows BVI can be a good tool for Alzheimer’s disease diagnosis. On the other hand, our findings of functional optical topography suggest that the left PFC can be a biomarker for discriminant analysis of schizophrenic diagnosis. The optical imaging offers a good potential tool for schizophrenia diagnosis with completely patient-oriented measurement.en_US
dc.description.sponsorship科技部zh_TW
dc.language.isozh_TWen_US
dc.title以近紅外光拓撲造影技術進行功能性/結構性前額葉影像研究zh_TW
dc.titleThe Investigation of Prefrontal Cortex Functional/Structural Imaging Based on Near-Infrared Optical Topographyen_US
dc.typePlanen_US
dc.contributor.department國立交通大學光電工程學系(所)zh_TW
Appears in Collections:Research Plans