|Title:||5-phenylpyridazinones - A serendipitous route from coumarins|
|Authors:||Ghate, Manjunath D.|
Jadhav, Vithal B.
Shastri, Lokesh A.
Kulkarni, Manohar V.
Kulkarni, Geetha M.
Department of Applied Chemistry
|Abstract:||A new route of the ring transformation has been discovered during the reaction of 4-bromomethylcoumarins with hydrazine hydrate leading to the formation of pharmacologically important pyridazinones in a single step with very high yields. These so obtained pyridazinones have the potential for further functional group interconversions. (C) 2008 Elsevier Ltd. All rights reserved.|
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