The Development of Light Transmission Improving Microprobe Array for Oxygen Saturation Measurement
|關鍵字:||近紅外光譜;皮膚組織;血氧濃度;微探針陣列;透光效率;穿透深度;Near Infrared Spectroscopy;Skin Organization;Oxygen Saturation;Microprobe Array;Light Transmission Efficiency;Penetrating Depth|
The purpose of this dissertation is to study the depth penetration and distribution of NIR in biological tissue. Here, a transparent microprobe array that was developed previously in our laboratory for EEG biopotential signal is used to demonstrate the improvement of light transmission efficiency with oxygen saturation measurement capability. The broad applications of NIR for biomedical research have been studied extensively. However, to pinpoint the position of the NIR in tissue becomes an import research issue in biomedical field. Therefore, in this dissertation, an adjustable laser light source system and a power meter was used to measure the depth penetration and distribution of NIR in pork tissue. In order to verify the experimental results, software simulations were performed and corresponding mathematical model were established. As indicated from the experimental results, skin is the key factor that reflected the light source which reduced the power penetrating into the tissue. A transparent microprobe array that was developed in our laboratory is used to dramatically overcome the above-mentioned drawback that greatly improved the transmission efficiency. Finally, the transparent microprobe is used to measure the oxygen concentration. Experimental results indicated that with less incident light power, we are able to obtain same level of oxygen concentration as in the case without the transparent microprobe.