The Study on the Strategy of Trial Run and Adjustment，Testing Procedures for Negative Pressure Animal Houses
|Keywords:||負壓;動物舍;ABSL-3;試車調整;檢測程序;negative pressure;animal house;ABSL-3;trial run and adjustment;testing procedures|
The negative pressure animal house is built to biosafety standards. It provides the environment for infected animal experiments and unsure the degree of influence confirmed infected animal experiments environment of the influence degree (such as genetically modified organisms) yet. The performance of animal houses not only could influence the accuracy of the experimental results, but also could protect the researchers’ safety and maintain the great environmental security of living beings. In Negative pressure animal houses, staff should dress in appropriate protection suits and follow standard operating procedures. In addition, the building structure, electromechanical, air conditioner, and experimental facilities should meet the secondary barriers. HVAC, one of the most important biosafety protections in negative pressure animal houses, would absolutely impact on the experimental results. This study is aimed to explore the possible problems of constructing in the negative pressure animal house. A real case is utilized to illustrate the possible potential impact and the proper solutions. It could be as a reference for the project personnel while preparing for installation and confronting the challenges.Because there are many factors of negative pressure values in animal houses, it is relatively complex and difficult during the course of taking a trial run and adjusting. Various kinds of performance are related to various degrees. It is impossible to adjust without analyzing the complete data. “Guide for the Biosafety of BSL-3 Laboratory 1.0-Edition” was issued by Center for Disease Control, Department of Health, in September of 2004. It demonstrates the regulations for laboratory facilities and test procedures. However, the test procedures are tedious and need to use the precise testing equipments. It takes a lot of time in testing and adjustment phase before the project is completed. This research simplifies the test steps and instruments. It saves a lot of time during the course of taking a trial run and adjusting.The testing data, comparing with the published data by the neutral organization, is reliable. The proposed solution could be widely utilized in environmental quality monitoring.
|Appears in Collections:||Thesis|