標題: Biomedical nanoparticle carriers with combined thermal and magnetic responses
作者: Liu, Ting-Yu
Hu, Shang-Hsiu
Liu, Dean-Mo
Chen, San-Yuan
Chen, I-Wei
材料科學與工程學系
Department of Materials Science and Engineering
關鍵字: Nanoparticles;Biomedical;Thermal response;Magnetic response;Drug delivery
公開日期: 1-二月-2009
摘要: Several biocompatible polymers are capable of large responses to small temperature changes around 37 degrees C In water, their responses include shrinkage and swelling as well as transitions in wettability. These properties have been harnessed for biomedical applications such as tissue engineering scaffolds and drug delivery carriers. A soft material/hard material hybrid in which a magnetic: metal or oxide is embedded in a temperature-responsive polymer matrix can combine the thermal sensitivity with magnetic signatures. Importantly, nanosizing such construct brings about new desirable features of extremely fast thermal response time, small magnetic hysteresis and enhanced magnetic susceptibility. Remote magnetic maneuvering and heating of the hybrid nanocolloids makes possible such applications as high-throughput enzyme separation and cell screening. Robust drug release on demand may also be obtained using these colloids and nanoparticle-derived thin film devices of combined thermal magnetic sensitivity. (C) 2008 Elsevier Ltd. All rights reserved.
URI: http://dx.doi.org/10.1016/j.nantod.2008.10.011
http://hdl.handle.net/11536/7673
ISSN: 1748-0132
DOI: 10.1016/j.nantod.2008.10.011
期刊: NANO TODAY
Volume: 4
Issue: 1
起始頁: 52
結束頁: 65
顯示於類別:期刊論文


文件中的檔案:

  1. 000262613400014.pdf