標題: A straightforward alpha-selective aromatic glycosylation and its application for stereospecific synthesis of 4-methylumbelliferyl alpha-T-antigen
作者: Chang, Shih-Sheng
Lin, Chun-Cheng
Li, Yaw-Kuen
Mong, Kwok-Kong Tony
應用化學系
Department of Applied Chemistry
關鍵字: Stereoselective;Aromatic;Glycosylation;Imidate;alpha-T-Antigen
公開日期: 10-三月-2009
摘要: A practical and efficient alpha-selective aromatic glycosylation with simple per-O-acetyl glycopyranosyl trichloroacetimidates is reported. The method is particularly effective for L-fucosyl and 2-azido-2-deoxy-D-galatosaminyl imidates, with which exclusive alpha-selectivity was achieved. The synthetic utility of this method was demonstrated in the stereoselective synthesis of 4-methylumbelliferyl alpha-T-antigen. (C) 2008 Elsevier Ltd. All rights reserved.
URI: http://dx.doi.org/10.1016/j.carres.2008.12.013
http://hdl.handle.net/11536/7494
ISSN: 0008-6215
DOI: 10.1016/j.carres.2008.12.013
期刊: CARBOHYDRATE RESEARCH
Volume: 344
Issue: 4
起始頁: 432
結束頁: 438
顯示於類別:期刊論文


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  1. 000264615900003.pdf