標題: Post-resuscitative clinical features in the first hour after achieving sustained ROSC predict the duration of survival in children with non-traumatic out-of-hospital cardiac arrest
作者: Lin, Yan-Ren
Li, Chao-Jui
Wu, Tung-Kung
Chang, Yu-Jun
Lai, Shih-Chang
Liu, Tzu-An
Hsiao, Ming-Hau
Chou, Chu-Chung
Chang, Chin-Fu
生物科技學系
Department of Biological Science and Technology
關鍵字: Out-of-hospital cardiac arrest;Return of spontaneous circulation;Post-resuscitative;Cardiac output;Children
公開日期: 1-Apr-2010
摘要: Aim of the study: Although sustained return of spontaneous circulation (ROSC) can be initially established after resuscitation from non-traumatic out-of-hospital cardiac arrest (OHCA) in some children, many of the children lose spontaneous circulation during hospital stay and do not survive to discharge. The aim of this study was to determine the clinical features during the first hour after ROSC that may predict survival to hospital discharge. Methods: We retrospectively evaluated the medical records of 228 children who presented to the emergency department without spontaneous circulation following non-traumatic OHCA during the period January 1996 to December 2008. Among these children, 80 achieved sustained ROSC for at least 20 min. The post-resuscitative clinical features during the first hour after achieving sustained ROSC that correlated with survival, median duration of survival, and death were analyzed. Results: Among the 80 children who achieved sustained ROSC for at least 20 min, 28 survived to hospital discharge and 6 had good neurologic outcomes (PCPC scale = 1 or 2). Post-resuscitative clinical features associated with survival included sinus cardiac rhythm (p = 0.012), normal heart rate (p = 0.008), normal blood pressure (p < 0.001), urine output > 1 ml/kg/h (p = 0.002), normal skin color (p = 0.016), lack of cardiopulmonary resuscitation (CPR)-induced rib fracture (p = 0.044), initial Glasgow Coma Scale score > 7 (p < 0.001), and duration of in-hospital CPR <= 10 min (p < 0.001). Furthermore, these variables were also significantly associated with the duration of survival (all p < 0.05). Conclusions: The most important predictors of survival to hospital discharge in children with OHCA who achieve sustained ROSC are a normal heart rate, normal blood pressure, and an initial urine output > 1 ml/kg/h. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
URI: http://dx.doi.org/10.1016/j.resuscitation.2010.01.006
http://hdl.handle.net/11536/5532
ISSN: 0300-9572
DOI: 10.1016/j.resuscitation.2010.01.006
期刊: RESUSCITATION
Volume: 81
Issue: 4
起始頁: 410
結束頁: 417
Appears in Collections:Articles


Files in This Item:

  1. 000276707200009.pdf