標題: Transparent microprobe array fabricated by MEMS hot embossing technology for photodynamic therapy application
作者: Hung, Chen-Chun
Chiou, Jin-Chern
Chang, Chih-Wei
電控工程研究所
Institute of Electrical and Control Engineering
關鍵字: MEMS;photodynamic therapy;needle array;hot embossing
公開日期: 10-五月-2010
摘要: This work describes a novel transparent micro-needle array for photodynamic therapy (PDT) applications. This micro-needle array, with 250 um in height and 35 um in diameter, was placed onto skin and penetrated the cuticle yet not reaching the corium layer, so as to avoid pain and bleeding but achieve superior light transmission efficiency. For PDT applications, this design can significantly reduce the required incident power and therefore avoid additional damage to surrounding healthy tissue. Practical in-vivo test on human skin demonstrates the improved power transmission efficiency (PTE) of two types of needle arrays is 1.41 and 1.71 times better than the condition without using micro-needle array.
URI: http://dx.doi.org/10.1587/elex.7.569
http://hdl.handle.net/11536/5410
ISSN: 1349-2543
DOI: 10.1587/elex.7.569
期刊: IEICE ELECTRONICS EXPRESS
Volume: 7
Issue: 9
起始頁: 569
結束頁: 576
顯示於類別:期刊論文


文件中的檔案:

  1. 000278375700002.pdf