標題: Multistep Microwave-Assisted Divergent Synthesis of Indolo-Fused Pyrazino-/Diazepinoquinoxalinones on PEG Support
作者: Lai, Jin-Ji
Salunke, Deepak B.
Sun, Chung-Ming
應用化學系
Department of Applied Chemistry
公開日期: 21-五月-2010
摘要: Synthesis of amino acid and indoline-substituted dinitrobenzene on a soluble polymer support (PEG) and its further reductive double-ring closure to afford structurally diverse indolo-fused pyrazino-/diazepinoquinoxalinones is described. Traceless synthesis of quinoxalinones coupled with application of the Pictet-Spengler-type condensation reaction furnished these novel scaffolds. These hitherto novel heterocycles are synthesized in shorter times under microwave irradiation conditions in comparison with that of classical reaction conditions.
URI: http://dx.doi.org/10.1021/ol100436r
http://hdl.handle.net/11536/5389
ISSN: 1523-7060
DOI: 10.1021/ol100436r
期刊: ORGANIC LETTERS
Volume: 12
Issue: 10
起始頁: 2174
結束頁: 2177
顯示於類別:期刊論文