標題: Protein Functionalized Nanodiamond Arrays
作者: Liu, Y. L.
Sun, K. W.
應用化學系
Department of Applied Chemistry
關鍵字: Nanodiamond;Biosensor;Self-assembled monolayer
公開日期: 1-六月-2010
摘要: Various nanoscale elements are currently being explored for bio-applications, such as in bio-images, bio-detection, and bio-sensors. Among them, nanodiamonds possess remarkable features such as low bio-cytotoxicity, good optical property in fluorescent and Raman spectra, and good photostability for bio-applications. In this work, we devise techniques to position functionalized nanodiamonds on self-assembled monolayer (SAMs) arrays adsorbed on silicon and ITO substrates surface using electron beam lithography techniques. The nanodiamond arrays were functionalized with lysozyme to target a certain biomolecule or protein specifically. The optical properties of the nanodiamond-protein complex arrays were characterized by a high throughput confocal microscope. The synthesized nanodiamond-lysozyme complex arrays were found to still retain their functionality in interacting with E. coli.
URI: http://dx.doi.org/10.1007/s11671-010-9600-7
http://hdl.handle.net/11536/5311
ISSN: 1931-7573
DOI: 10.1007/s11671-010-9600-7
期刊: NANOSCALE RESEARCH LETTERS
Volume: 5
Issue: 6
起始頁: 1045
結束頁: 1050
顯示於類別:期刊論文


文件中的檔案:

  1. 000278096000020.pdf