標題: A Newborn Screening System Based on Service-Oriented Architecture Embedded Support Vector Machine
作者: Hsu, Kai-Ping
Hsieh, Sung-Huai
Hsieh, Sheau-Ling
Cheng, Po-Hsun
Weng, Yung-Ching
Wu, Jang-Hung
Lai, Feipei
資訊技術服務中心
Information Technology Services Center
關鍵字: Web services;Newborn screening;Service-Oriented Architecture;Tandem mass spectrometry;Support Vector Machine
公開日期: 1-Oct-2010
摘要: The clinical symptoms of metabolic disorders are rarely apparent during the neonatal period, and if they are not treated earlier, irreversible damages, such as mental retardation or even death, may occur. Therefore, the practice of newborn screening is essential to prevent permanent disabilities in newborns. In the paper, we design, implement a newborn screening system using Support Vector Machine (SVM) classifications. By evaluating metabolic substances data collected from tandem mass spectrometry (MS/MS), we can interpret and determine whether a newborn has a metabolic disorder. In addition, National Taiwan University Hospital Information System (NTUHIS) has been developed and implemented to integrate heterogeneous platforms, protocols, databases as well as applications. To expedite adapting the diversities, we deploy Service-Oriented Architecture (SOA) concepts to the newborn screening system based on web services. The system can be embedded seamlessly into NTUHIS.
URI: http://dx.doi.org/10.1007/s10916-009-9305-6
http://hdl.handle.net/11536/32092
ISSN: 0148-5598
DOI: 10.1007/s10916-009-9305-6
期刊: JOURNAL OF MEDICAL SYSTEMS
Volume: 34
Issue: 5
起始頁: 899
結束頁: 907
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