標題: Micro-channel fabrication by femtosecond laser to arrange neuronal cells on multi-electrode arrays
作者: Hosokawa, Chie
Kudoh, Suguru N.
Suzuki, Mariko
Kiyohara, Ai
Hosokawa, Yoichiroh
Okano, Kazunori
Masuhara, Hiroshi
Taguchi, Takahisa
應用化學系
應用化學系分子科學碩博班
Department of Applied Chemistry
Institute of Molecular science
公開日期: 1-Nov-2010
摘要: We propose and demonstrate micro-channel fabrication by femtosecond-laser processing to arrange neuronal cells on multi-electrode arrays (MEAs). When neuronal cells were seeded in the micro-channels on MEAs, they elongated their neurites along the channel and finally formed the network patterned on MEAs. The spontaneous electrical activity of the neuronal networks on MEAs was evaluated by using electrophysiological systems, indicating that patterned network was functionally activated along the channels. The present method is applicable to analyze network dynamics of living neuronal cells patterned artificially.
URI: http://dx.doi.org/10.1007/s00339-010-5836-4
http://hdl.handle.net/11536/32048
ISSN: 0947-8396
DOI: 10.1007/s00339-010-5836-4
期刊: APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
Volume: 101
Issue: 2
起始頁: 423
結束頁: 428
Appears in Collections:Articles


Files in This Item:

  1. 000283088600034.pdf