標題: Finding regularity in various types of secondary protein structures
作者: Chu, YW
Yang, JM
生物科技學系
資訊工程學系
Department of Biological Science and Technology
Department of Computer Science
關鍵字: secondary protein structure;schema;steady-state genetic algorithm;rule extraction;sequence alignment;substitution matrix;voting mechanism;sequential pattern
公開日期: 1-Nov-2003
摘要: Protein function is structurally determined, but analyzing the structure of a protein is both difficult and time-consuming. The authors look at the natural instincts of protein secondary structures, which used to be analyzed in terms of their statistical relationship with a single amino acid. Several schemas are offered for identifying regular patterns among various types of secondary protein structures. The schemas employ genetic algorithms based on a steady-state strategy. Two disjunctive data sets were used to verify fitness. The paper concludes with some illustrations of significant schemas produced as part of this study, with brief explanations of their significance.
URI: http://hdl.handle.net/11536/27422
ISSN: 1016-2364
期刊: JOURNAL OF INFORMATION SCIENCE AND ENGINEERING
Volume: 19
Issue: 6
起始頁: 943
結束頁: 952
Appears in Collections:Articles


Files in This Item:

  1. 000186810000004.pdf