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dc.contributor.authorYang, YLen_US
dc.contributor.authorCheng, HHen_US
dc.contributor.authorLo, HJen_US
dc.date.accessioned2014-12-08T15:38:37Z-
dc.date.available2014-12-08T15:38:37Z-
dc.date.issued2004-09-01en_US
dc.identifier.issn0924-8579en_US
dc.identifier.urihttp://hdl.handle.net/11536/26422-
dc.description.abstractThe activity of voriconazole was determined against 285 Candida species consisting of 53 resistant isolates, 43 susceptible-dose dependent and 189 isolates susceptible to fluconazole. The MIC50 and MIC90 to fluconazole were 8 and 64 mg/l, respectively. The range of minimum inhibitory concentrations (MICs) to voriconazole was from 0.0325 to 2 mg/l and the MIC50 and MIC90 were 0.125 and 0.5 mgA, respectively. Only 3 of 285 tested isolates had MICs to voriconazole equal to 2 mg/l. A total of 38 isolates, consisted of 3 Candida albicans, 5 Candida krusei, 7 Candida tropicalis and 21 Candida glabrata, had MICs greater than or equal to 0.5 mg/l to voriconazole. There was correlation between the susceptibility to fluconazole and voriconazole. (C) 2004 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.en_US
dc.language.isoen_USen_US
dc.subjectCandida speciesen_US
dc.subjectvoriconazoleen_US
dc.subjectfluconazoleen_US
dc.subjectresistanceen_US
dc.titleIn vitro activity of voriconazole against Candida species isolated in Taiwanen_US
dc.typeArticleen_US
dc.identifier.journalINTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTSen_US
dc.citation.volume24en_US
dc.citation.issue3en_US
dc.citation.spage294en_US
dc.citation.epage296en_US
dc.contributor.department生物科技學系zh_TW
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.identifier.wosnumberWOS:000224070400016-
dc.citation.woscount11-
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