標題: In vitro activity of voriconazole against Candida species isolated in Taiwan
作者: Yang, YL
Cheng, HH
Lo, HJ
生物科技學系
Department of Biological Science and Technology
關鍵字: Candida species;voriconazole;fluconazole;resistance
公開日期: 1-Sep-2004
摘要: The activity of voriconazole was determined against 285 Candida species consisting of 53 resistant isolates, 43 susceptible-dose dependent and 189 isolates susceptible to fluconazole. The MIC50 and MIC90 to fluconazole were 8 and 64 mg/l, respectively. The range of minimum inhibitory concentrations (MICs) to voriconazole was from 0.0325 to 2 mg/l and the MIC50 and MIC90 were 0.125 and 0.5 mgA, respectively. Only 3 of 285 tested isolates had MICs to voriconazole equal to 2 mg/l. A total of 38 isolates, consisted of 3 Candida albicans, 5 Candida krusei, 7 Candida tropicalis and 21 Candida glabrata, had MICs greater than or equal to 0.5 mg/l to voriconazole. There was correlation between the susceptibility to fluconazole and voriconazole. (C) 2004 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
URI: http://hdl.handle.net/11536/26422
ISSN: 0924-8579
期刊: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Volume: 24
Issue: 3
起始頁: 294
結束頁: 296
Appears in Collections:Articles


Files in This Item:

  1. 000224070400016.pdf