標題: A "turn on/off" scorpion biosensor targeting point mutation of SMN genes for diagnosis of spinal muscular atrophy
作者: Chen, Chung-An
Wang, Chun-Chi
Chen, Yen-Ling
Jong, Yuh-Jyh
Wu, Shou-Mei
生物科技學院
College of Biological Science and Technology
公開日期: 2014
摘要: A "turn on/off\'\' biosensor for diagnosis of exon 7 of the SMN1 gene was developed by employing a "scorpion primer\'\'. This scorpion primer was based on the principle of fluorescence resonance energy transfer using a fluorophore, a blocker and a quencher. It was successfully applied to detect 10 volunteer samples, and not only to in vitro testing.
URI: http://hdl.handle.net/11536/24568
http://dx.doi.org/10.1039/c4cc03472d
ISSN: 1359-7345
DOI: 10.1039/c4cc03472d
期刊: CHEMICAL COMMUNICATIONS
Volume: 50
Issue: 59
起始頁: 8069
結束頁: 8072
顯示於類別:期刊論文


文件中的檔案:

  1. 000338439700039.pdf