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dc.contributor.authorHsu, Ming-Huaen_US
dc.contributor.authorChuang, Hongen_US
dc.contributor.authorCheng, Fong-Yuen_US
dc.contributor.authorHuang, Ying-Peien_US
dc.contributor.authorHan, Chien-Chungen_US
dc.contributor.authorChen, Jiun-Yuen_US
dc.contributor.authorHuang, Su-Chinen_US
dc.contributor.authorChen, Jen-Kunen_US
dc.contributor.authorWu, Dian-Syueen_US
dc.contributor.authorChu, Hsueh-Liangen_US
dc.contributor.authorChang, Chia-Chingen_US
dc.date.accessioned2014-12-08T15:36:05Z-
dc.date.available2014-12-08T15:36:05Z-
dc.date.issued2014-05-28en_US
dc.identifier.issn1944-8244en_US
dc.identifier.urihttp://dx.doi.org/10.1021/am500324zen_US
dc.identifier.urihttp://hdl.handle.net/11536/24417-
dc.description.abstractAn efficient method for modifying the surface of detonation nanodiamonds (5 and 100 nm) with thiol groups (-SH) by using an organic chemistry strategy is presented herein. Thiolated nanodiamonds were characterized by spectroscopic techniques, and the atomic percentage of sulfur was analyzed by elemental analysis and X-ray photoelectron spectroscopy. The conjugation between thiolated nanodiamonds and gold nanoparticles was elucidated by transmission electron microscopy and UV-vis spectrometry. Moreover, the material did not show significant cytotoxicity to the human lung carcinoma cell line and may prospectively be applied in bioconjugated technology. The new method that we elucidated may significantly improve the approach to surface modification of detonation nanodiamonds and build up a new platform for the application of nanodiamonds.en_US
dc.language.isoen_USen_US
dc.subjectthiolateden_US
dc.subjectnanodiamonden_US
dc.subjectdetonation nanodiamonden_US
dc.subjectsurface modificationen_US
dc.subjectthiolated nanodiamonden_US
dc.subjectfunctionalized nanodiamonden_US
dc.titleDirectly Thiolated Modification onto the Surface of Detonation Nanodiamondsen_US
dc.typeArticleen_US
dc.identifier.doi10.1021/am500324zen_US
dc.identifier.journalACS APPLIED MATERIALS & INTERFACESen_US
dc.citation.volume6en_US
dc.citation.issue10en_US
dc.citation.spage7198en_US
dc.citation.epage7203en_US
dc.contributor.department生物科技學系zh_TW
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.identifier.wosnumberWOS:000336639200028-
dc.citation.woscount1-
Appears in Collections:Articles


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