標題: Directly Thiolated Modification onto the Surface of Detonation Nanodiamonds
作者: Hsu, Ming-Hua
Chuang, Hong
Cheng, Fong-Yu
Huang, Ying-Pei
Han, Chien-Chung
Chen, Jiun-Yu
Huang, Su-Chin
Chen, Jen-Kun
Wu, Dian-Syue
Chu, Hsueh-Liang
Chang, Chia-Ching
生物科技學系
Department of Biological Science and Technology
關鍵字: thiolated;nanodiamond;detonation nanodiamond;surface modification;thiolated nanodiamond;functionalized nanodiamond
公開日期: 28-五月-2014
摘要: An efficient method for modifying the surface of detonation nanodiamonds (5 and 100 nm) with thiol groups (-SH) by using an organic chemistry strategy is presented herein. Thiolated nanodiamonds were characterized by spectroscopic techniques, and the atomic percentage of sulfur was analyzed by elemental analysis and X-ray photoelectron spectroscopy. The conjugation between thiolated nanodiamonds and gold nanoparticles was elucidated by transmission electron microscopy and UV-vis spectrometry. Moreover, the material did not show significant cytotoxicity to the human lung carcinoma cell line and may prospectively be applied in bioconjugated technology. The new method that we elucidated may significantly improve the approach to surface modification of detonation nanodiamonds and build up a new platform for the application of nanodiamonds.
URI: http://dx.doi.org/10.1021/am500324z
http://hdl.handle.net/11536/24417
ISSN: 1944-8244
DOI: 10.1021/am500324z
期刊: ACS APPLIED MATERIALS & INTERFACES
Volume: 6
Issue: 10
起始頁: 7198
結束頁: 7203
顯示於類別:期刊論文


文件中的檔案:

  1. 000336639200028.pdf