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dc.contributor.authorHsu, Sheng-Daen_US
dc.contributor.authorTseng, Yu-Tingen_US
dc.contributor.authorShrestha, Sirjanaen_US
dc.contributor.authorLin, Yu-Lingen_US
dc.contributor.authorKhaleel, Anasen_US
dc.contributor.authorChou, Chih-Hungen_US
dc.contributor.authorChu, Chao-Fangen_US
dc.contributor.authorHuang, Hsi-Yuanen_US
dc.contributor.authorLin, Ching-Minen_US
dc.contributor.authorHo, Shu-Yien_US
dc.contributor.authorJian, Ting-Yanen_US
dc.contributor.authorLin, Feng-Maoen_US
dc.contributor.authorChang, Tzu-Haoen_US
dc.contributor.authorWeng, Shun-Longen_US
dc.contributor.authorLiao, Kuang-Wenen_US
dc.contributor.authorLiao, I-Enen_US
dc.contributor.authorLiu, Chun-Chien_US
dc.contributor.authorHuang, Hsien-Daen_US
dc.date.accessioned2014-12-08T15:35:09Z-
dc.date.available2014-12-08T15:35:09Z-
dc.date.issued2014-01-01en_US
dc.identifier.issn0305-1048en_US
dc.identifier.urihttp://dx.doi.org/10.1093/nar/gkt1266en_US
dc.identifier.urihttp://hdl.handle.net/11536/23857-
dc.description.abstractMicroRNAs (miRNAs) are small non-coding RNA molecules capable of negatively regulating gene expression to control many cellular mechanisms. The miRTarBase database (http://mirtarbase.mbc.nctu.edu.tw/) provides the most current and comprehensive information of experimentally validated miRNA-target interactions. The database was launched in 2010 with data sources for >100 published studies in the identification of miRNA targets, molecular networks of miRNA targets and systems biology, and the current release (2013, version 4) includes significant expansions and enhancements over the initial release (2010, version 1). This article reports the current status of and recent improvements to the database, including (i) a 14-fold increase to miRNA-target interaction entries, (ii) a miRNA-target network, (iii) expression profile of miRNA and its target gene, (iv) miRNA target-associated diseases and (v) additional utilities including an upgrade reminder and an error reporting/user feedback system.en_US
dc.language.isoen_USen_US
dc.titlemiRTarBase update 2014: an information resource for experimentally validated miRNA-target interactionsen_US
dc.typeArticleen_US
dc.identifier.doi10.1093/nar/gkt1266en_US
dc.identifier.journalNUCLEIC ACIDS RESEARCHen_US
dc.citation.volume42en_US
dc.citation.issueD1en_US
dc.citation.spageD78en_US
dc.citation.epageD85en_US
dc.contributor.department生物科技學系zh_TW
dc.contributor.department生物資訊及系統生物研究所zh_TW
dc.contributor.department分子醫學與生物工程研究所zh_TW
dc.contributor.departmentMolecular Bioinformatics Centerzh_TW
dc.contributor.departmentDepartment of Biological Science and Technologyen_US
dc.contributor.departmentInstitude of Bioinformatics and Systems Biologyen_US
dc.contributor.departmentInstitute of Molecular Medicine and Bioengineeringen_US
dc.contributor.departmentMolecular Bioinformatics Centeren_US
dc.identifier.wosnumberWOS:000331139800013-
dc.citation.woscount29-
Appears in Collections:Articles


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