Title: Odor identification and cognitive function in the Beaver Dam Offspring Study
Authors: Schubert, Carla R.
Cruickshanks, Karen J.
Fischer, Mary E.
Huang, Guan-Hua
Klein, Ronald
Pankratz, Nathan
Zhong, Wenjun
Nondahl, David M.
Institute of Statistics
Keywords: Olfaction;Odor identification;Cognitive function;Executive function;Epidemiology
Issue Date: 19-Aug-2013
Abstract: Olfactory impairment is associated with cognitive impairment in older adults but less is known about the association of olfactory impairment and cognitive function in middle-aged adults. The association between olfactory impairment and cognitive function tests of attention, processing speed, and executive and psychomotor function was explored in 2837 participants (21-84 years; mean age 49 years) in the Beaver Dam Offspring Study. Among middle-aged participants (aged 35-64 years), those with impairment on an odor identification test took significantly longer to complete the Trail Making Test (TMT-A and TMT-B) and the Grooved Peg Board (GPB) test, than those without olfactory impairment in regression models adjusted for multiple factors. Similar results were found for the TMT-A and TMT-B, but not the GPB, in the whole cohort. Olfactory impairment was associated with poorer performance on cognitive function tests in a primarily middle-aged cohort.
URI: http://dx.doi.org/10.1080/13803395.2013.809701
ISSN: 1380-3395
DOI: 10.1080/13803395.2013.809701
Volume: 35
Issue: 7
Begin Page: 669
End Page: 676
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