|標題:||Odor identification and cognitive function in the Beaver Dam Offspring Study|
|作者:||Schubert, Carla R.|
Cruickshanks, Karen J.
Fischer, Mary E.
Nondahl, David M.
Institute of Statistics
|關鍵字:||Olfaction;Odor identification;Cognitive function;Executive function;Epidemiology|
|摘要:||Olfactory impairment is associated with cognitive impairment in older adults but less is known about the association of olfactory impairment and cognitive function in middle-aged adults. The association between olfactory impairment and cognitive function tests of attention, processing speed, and executive and psychomotor function was explored in 2837 participants (21-84 years; mean age 49 years) in the Beaver Dam Offspring Study. Among middle-aged participants (aged 35-64 years), those with impairment on an odor identification test took significantly longer to complete the Trail Making Test (TMT-A and TMT-B) and the Grooved Peg Board (GPB) test, than those without olfactory impairment in regression models adjusted for multiple factors. Similar results were found for the TMT-A and TMT-B, but not the GPB, in the whole cohort. Olfactory impairment was associated with poorer performance on cognitive function tests in a primarily middle-aged cohort.|
|期刊:||JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY|