標題: One-Pot, Two-Step Synthesis of Imidazo[1,2-a]benzimidazoles via A Multicomponent [4+1] Cycloaddition Reaction
作者: Hsiao, Ya-Shan
Narhe, Bharat D.
Chang, Ying-Sheng
Sun, Chung-Ming
應用化學系
Department of Applied Chemistry
關鍵字: microwave irradiation;[4+1] cycloaddition;imidazo[1,2-a]benzimidazoles;three-component reaction
公開日期: 1-十月-2013
摘要: A one-pot, two-step synthesis of imidazo[1,2-a]benzimidazoles has been achieved by a three-component reaction of 2-aminobenzimidazoles with an aromatic aldehyde and an isocyanide. The reaction involving condensation of 2-aminobenzimidazole with an aldehyde is run under microwave activation to generate an imine intermediate under basic conditions which then undergoes [4 + 1] cycloaddition with an isocyanide.
URI: http://dx.doi.org/10.1021/co400075z
http://hdl.handle.net/11536/23007
ISSN: 2156-8952
DOI: 10.1021/co400075z
期刊: ACS COMBINATORIAL SCIENCE
Volume: 15
Issue: 10
起始頁: 551
結束頁: 555
顯示於類別:期刊論文


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