Title: Using nanopillars of silicon oxide as a versatile platform for visualizing a selective immunosorbent
Authors: Chen, Jem-Kun
Zhou, Gang-Yan
Huang, Chih-Feng
Ko, Fu-Hsiang
Department of Applied Chemistry
Issue Date: 24-Jun-2013
Abstract: In this study, we fabricated nanopillar arrays of silicon oxide for use as two-dimensional periodic relief gratings (2DPRGs) on Si surfaces. We deposited antibodies onto the pillar surfaces of 2DPRGs modified with protein G to obtain optical detectors that were specific for the targeted antigen; the antigen units that filled the spaces between the nanopillars of the 2DPRG lead to a dramatic change in the pillar scale. The effective refractive index (n(eff)) of the 2DPRGs was related to the pillar scale of the 2DPRG; after coupling of the antigen, a color change from pure green to orange was observable. (C) 2013 AIP Publishing LLC.
URI: http://dx.doi.org/10.1063/1.4812340
ISSN: 0003-6951
DOI: 10.1063/1.4812340
Volume: 102
Issue: 25
End Page: 
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