Title: A CMOS Power-Efficient Low-Noise Current-Mode Front-End Amplifier for Neural Signal Recording
Authors: Wu, Chung-Yu
Chen, Wei-Ming
Kuo, Liang-Ting
Department of Electronics Engineering and Institute of Electronics
Biomedical Electronics Translational Research Center
Keywords: Current-mode;front-end;low-noise low power design;neural recording;offset cancellation
Issue Date: 1-Apr-2013
Abstract: In this paper, a new current-mode front-end amplifier (CMFEA) for neural signal recording systems is proposed. In the proposed CMFEA, a current-mode preamplifier with an active feedback loop operated at very low frequency is designed as the first gain stage to bypass any dc offset current generated by the electrode-tissue interface and to achieve a low high-pass cutoff frequency below 0.5 Hz. No reset signal or ultra-large pseudo resistor is required. The current-mode preamplifier has low dc operation current to enhance low-noise performance and decrease power consumption. A programmable current gain stage is adopted to provide adjustable gain for adaptive signal scaling. A following current-mode filter is designed to adjust the low-pass cutoff frequency for different neural signals. The proposed CMFEA is designed and fabricated in 0.18-mu m CMOS technology and the area of the core circuit is 0.076 mm(2). The measured high-pass cutoff frequency is as low as 0.3 Hz and the low-pass cutoff frequency is adjustable from 1 kHz to 10 kHz. The measured maximum current gain is 55.9 dB. The measured input-referred current noise density is 153fA/root Hz, and the power consumption is 13 mu W at 1-V power supply. The fabricated CMFEA has been successfully applied to the animal test for recording the seizure ECoG of Long-Evan rats.
URI: http://dx.doi.org/10.1109/TBCAS.2013.2256422
ISSN: 1932-4545
DOI: 10.1109/TBCAS.2013.2256422
Volume: 7
Issue: 2
Begin Page: 107
End Page: 114
Appears in Collections:Articles

Files in This Item:

  1. 000318797100002.pdf