標題: Highly Sensitive Ammonia Sensor with Organic Vertical Nanojunctions for Noninvasive Detection of Hepatic Injury
作者: Dai, Ming-Zhi
Lin, Yi-Lo
Lin, Hung-Cheng
Zan, Hsiao-Wen
Chang, Kai-Ting
Meng, Hsin-Fei
Liao, Jiunn-Wang
Tsai, May-Jywan
Cheng, Henrich
物理研究所
光電工程學系
Institute of Physics
Department of Photonics
公開日期: 19-Mar-2013
摘要: We successfully demonstrate the first solid-state sensor to have reliable responses to breath ammonia of rat. For thioacetamide (TAA)-induced hepatopathy rats, we observe that the proposed sensor can detect liver that undergoes acute-moderate hepatopathy with a p-value less than 0.05. The proposed sensor is an organic diode with vertical nanojunctions produced by using low-cost colloidal lithography. Its simple structure and low production cost facilitates the development of point-of-care technology. We also anticipate that the study is a starting point for investigating sophisticated breath-ammonia-related disease models.
URI: http://dx.doi.org/10.1021/ac303100k
http://hdl.handle.net/11536/21375
ISSN: 0003-2700
DOI: 10.1021/ac303100k
期刊: ANALYTICAL CHEMISTRY
Volume: 85
Issue: 6
起始頁: 3110
結束頁: 3117
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