標題: Label-free detection of DNA hybridization using transistors based on CVD grown graphene
作者: Chen, Tzu-Yin
Phan Thi Kim Loan
Hsu, Chang-Lung
Lee, Yi-Hsien
Wang, Jacob Tse-Wei
Wei, Kung-Hwa
Lin, Cheng-Te
Li, Lain-Jong
材料科學與工程學系
Department of Materials Science and Engineering
關鍵字: Label-free detection;Liquid-gated transistors;DNA sensing;CVD graphene;Gold-transfer method
公開日期: 15-三月-2013
摘要: The high transconductance and low noise of graphene-based field-effect transistors based on large-area monolayer graphene produced by chemical vapor deposition are used for label-free electrical detection of DNA hybridization. The gate materials, buffer concentration and surface condition of graphene have been optimized to achieve the DNA detection sensitivity as low as 1 pM (10(-12) M), which is more sensitive than the existing report based on few-layer graphene. The graphene films obtained using conventional PMMA-assisted transfer technique exhibits PMMA residues, which degrade the sensing performance of graphene. We have demonstrated that the sensing performance of the graphene samples prepared by gold-transfer is largely enhanced (by 125%). (C) 2012 Elsevier B.V. All rights reserved.
URI: http://dx.doi.org/10.1016/j.bios.2012.07.059
http://hdl.handle.net/11536/20999
ISSN: 0956-5663
DOI: 10.1016/j.bios.2012.07.059
期刊: BIOSENSORS & BIOELECTRONICS
Volume: 41
Issue: 
起始頁: 103
結束頁: 109
顯示於類別:期刊論文


文件中的檔案:

  1. 000314191300012.pdf