Title: Design and synthesis of triazolyl coumarins as Hg2+ selective fluorescent chemosensors
Authors: Ho, I-Ting
Lai, Ting-Ling
Wu, Ren-Tsung
Tsai, Ming-Tsung
Wu, Chun-Ming
Lee, Gene-Hsiang
Chung, Wen-Sheng
Department of Applied Chemistry
Issue Date: 2012
Abstract: A series of triazolyl coumarin derivatives L1-L4, with and without spacer groups between the coumarin and the triazole groups, were synthesized as fluorescent sensors to study their binding ability and selectivity toward metal ions. Ligand L3, which contains an acetyl linker between the triazole and the coumarin, exhibited a high selectivity toward Hg2+ in polar protic solvents MeOH-CHCl3 (9 : 1, v/v) with fluorescent enhancement, furthermore, it was found to bind two Hg2+ at a high concentration (>12.5 mM) of Hg(ClO4)(2). In contrast, L4, in which position 4 of the triazole unit was replaced by a benzyl group instead of the 4-tert-butylphenoxymethyl group used in L1-L3, showed a binding stoichiometry toward only one Hg2+. On the basis of the fluorescent sensing, IR, and H-1 NMR titration results of ligands L1-L4, we proposed that not only the acetyl C=O but also the ether group of the 4-tert-butylphenoxymethyl of L3 assisted the triazole nitrogen atoms in the complexation of Hg2+ to form a 1 : 2 complex (L3 center dot(Hg2+)(2)).
URI: http://hdl.handle.net/11536/20897
ISSN: 0003-2654
DOI: 10.1039/c2an36076d
Journal: ANALYST
Volume: 137
Issue: 24
Begin Page: 5770
End Page: 5776
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