標題: Decision tree-based learning to predict patient controlled analgesia consumption and readjustment
作者: Hu, Yuh-Jyh
Ku, Tien-Hsiung
Jan, Rong-Hong
Wang, Kuochen
Tseng, Yu-Chee
Yang, Shu-Fen
分子醫學與生物工程研究所
資訊工程學系
Institute of Molecular Medicine and Bioengineering
Department of Computer Science
關鍵字: Classification;Data cleaning;Decision tree-based learning;Pain management;Patient Controlled Analgesia (PCA)
公開日期: 14-Nov-2012
摘要: Background: Appropriate postoperative pain management contributes to earlier mobilization, shorter hospitalization, and reduced cost. The under treatment of pain may impede short-term recovery and have a detrimental long-term effect on health. This study focuses on Patient Controlled Analgesia (PCA), which is a delivery system for pain medication. This study proposes and demonstrates how to use machine learning and data mining techniques to predict analgesic requirements and PCA readjustment. Methods: The sample in this study included 1099 patients. Every patient was described by 280 attributes, including the class attribute. In addition to commonly studied demographic and physiological factors, this study emphasizes attributes related to PCA. We used decision tree-based learning algorithms to predict analgesic consumption and PCA control readjustment based on the first few hours of PCA medications. We also developed a nearest neighbor-based data cleaning method to alleviate the class-imbalance problem in PCA setting readjustment prediction. Results: The prediction accuracies of total analgesic consumption (continuous dose and PCA dose) and PCA analgesic requirement (PCA dose only) by an ensemble of decision trees were 80.9% and 73.1%, respectively. Decision tree-based learning outperformed Artificial Neural Network, Support Vector Machine, Random Forest, Rotation Forest, and Naive Bayesian classifiers in analgesic consumption prediction. The proposed data cleaning method improved the performance of every learning method in this study of PCA setting readjustment prediction. Comparative analysis identified the informative attributes from the data mining models and compared them with the correlates of analgesic requirement reported in previous works. Conclusion: This study presents a real-world application of data mining to anesthesiology. Unlike previous research, this study considers a wider variety of predictive factors, including PCA demands over time. We analyzed PCA patient data and conducted several experiments to evaluate the potential of applying machine-learning algorithms to assist anesthesiologists in PCA administration. Results demonstrate the feasibility of the proposed ensemble approach to postoperative pain management.
URI: http://hdl.handle.net/11536/20618
ISSN: 1472-6947
期刊: BMC MEDICAL INFORMATICS AND DECISION MAKING
Volume: 12
Issue: 
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