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dc.contributor.authorChung, Tsai-Wenen_US
dc.contributor.authorChen, Chih-Hauen_US
dc.contributor.authorLin, Chu-Chungen_US
dc.contributor.authorWu, Hsien-Jenen_US
dc.contributor.authorSun, Chung-Mingen_US
dc.contributor.authorChung, Wen-Shengen_US
dc.date.accessioned2014-12-08T15:24:21Z-
dc.date.available2014-12-08T15:24:21Z-
dc.date.issued2012-08-01en_US
dc.identifier.issn1381-1991en_US
dc.identifier.urihttp://dx.doi.org/10.1007/s11030-012-9380-3en_US
dc.identifier.urihttp://hdl.handle.net/11536/16915-
dc.description.abstractA novel and efficient cleavage reagent, trimethyl aluminum, for traceless sulfinate-functionalized resin has been developed. The synthesis of sulfonamide and urea derivatives via a traceless solid-phase sulfone linker strategy through six synthetic steps comprising utilization of trimethyl aluminum as a novel cleavage reagent was also established. An insight of the plausible mechanism of the cleavage reaction was discussed.en_US
dc.language.isoen_USen_US
dc.subjectTrimethyl aluminumen_US
dc.subjectTracelessen_US
dc.subjectSolid-phase synthesisen_US
dc.subjectSulfone linkeren_US
dc.subjectSulfinate-functionalized resinen_US
dc.subjectSulfonamidesen_US
dc.subjectUreasen_US
dc.titleExploring a sulfone linker utilizing trimethyl aluminum as a cleavage reagent: solid-phase synthesis of sulfonamides and ureasen_US
dc.typeArticleen_US
dc.identifier.doi10.1007/s11030-012-9380-3en_US
dc.identifier.journalMOLECULAR DIVERSITYen_US
dc.citation.volume16en_US
dc.citation.issue3en_US
dc.citation.spage463en_US
dc.citation.epage476en_US
dc.contributor.department應用化學系zh_TW
dc.contributor.departmentDepartment of Applied Chemistryen_US
dc.identifier.wosnumberWOS:000308555600005-
dc.citation.woscount0-
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