|Title:||Dynamic regulation on energy landscape evolution of single-molecule protein by conformational fluctuation|
|Authors:||Lin, Chien Y.|
Huang, Jung Y.
Department of Photonics
|Abstract:||We formalize a theory to help explore the effect of conformational fluctuation on the energy landscape evolution of single-molecule protein. Using this formalization, we investigate the photon emission from single photoactivated fluorescent protein. A bimodal regulation on the energy landscape evolution was discovered, and its origin was attributed to slow conformational fluctuations of the protein matrix.|
|Journal:||PHYSICAL REVIEW E|
|Appears in Collections:||Articles|