|標題:||Dynamic regulation on energy landscape evolution of single-molecule protein by conformational fluctuation|
|作者:||Lin, Chien Y.|
Huang, Jung Y.
Department of Photonics
|摘要:||We formalize a theory to help explore the effect of conformational fluctuation on the energy landscape evolution of single-molecule protein. Using this formalization, we investigate the photon emission from single photoactivated fluorescent protein. A bimodal regulation on the energy landscape evolution was discovered, and its origin was attributed to slow conformational fluctuations of the protein matrix.|
|期刊:||PHYSICAL REVIEW E|