標題: A computerized system of nail-fold capillaroscopy for dry eye disease diagnosis
作者: Hou, Mark C.
Huang, Sheng-Chieh
Wang, Hui-Min
Tseng, Cheng-Lung
Lo, Lun-Chien
Chen, Ying-Ling
電機工程學系
Department of Electrical and Computer Engineering
關鍵字: Nail-fold capillaroscopy;Image processing;Dry eye disease
公開日期: 1-十二月-2012
摘要: Nail-fold Capillaroscopy is a convenient and non-invasive tool to evaluate peripheral circulation. Rheumatic diseases such as Raynaud's disease and systemic sclerosis are investigated mostly by nail-fold capillaroscopy. However, it has not been used popularly due to the lack of golden standard in both measurement procedure and objective quantity analysis. This study proposes a computerized system of nail-fold capillaroscopy (CNC). CNC includes standard measurement procedures and three criterions of microcirculation which are capillary density, capillary width and blood flow velocity. CNC is applied to the images of 36 normal subjects and seven patients of dry eye disease (DED). We found density and width of afferent capillary were the better parameters to identify DED (p < 0.05). CNC could be a good auxiliary diagnostic tool for DED.
URI: http://dx.doi.org/10.1007/s11045-012-0177-4
http://hdl.handle.net/11536/16785
ISSN: 0923-6082
DOI: 10.1007/s11045-012-0177-4
期刊: MULTIDIMENSIONAL SYSTEMS AND SIGNAL PROCESSING
Volume: 23
Issue: 4
起始頁: 515
結束頁: 524
顯示於類別:期刊論文


文件中的檔案:

  1. 000306800600007.pdf