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dc.contributor.authorChien, C-C.en_US
dc.contributor.authorCheng, C-C.en_US
dc.contributor.authorChen, H. H.en_US
dc.contributor.authorHwu, Y.en_US
dc.contributor.authorChu, Y. S.en_US
dc.contributor.authorPetibois, C.en_US
dc.contributor.authorChen, A.en_US
dc.contributor.authorChing, Y-T.en_US
dc.contributor.authorMargaritondo, G.en_US
dc.date.accessioned2014-12-08T15:24:02Z-
dc.date.available2014-12-08T15:24:02Z-
dc.date.issued2012-09-01en_US
dc.identifier.issn1618-2642en_US
dc.identifier.urihttp://hdl.handle.net/11536/16707-
dc.description.abstract"We demonstrate that, with appropriate staining, high-resolution X-ray microscopy can image complicated tissue structures-cerebellum and liver-and resolve large or small amounts of Au nanoparticles in these tissues. Specifically, images of tumor tissue reveal high concentrations of accumulated Au nanoparticles. PEG (poly(ethylene glycol)) coating is quite effective in enhancing this accumulation and significantly modifies the mechanism of uptake by reticuloendothelial system (RES) organs."en_US
dc.language.isoen_USen_US
dc.subjectHigh resolution X-ray microscopyen_US
dc.subjectNanoparticlesen_US
dc.subject3D tissue imagingen_US
dc.titleX-ray microscopy and tomography detect the accumulation of bare and PEG-coated gold nanoparticles in normal and tumor mouse tissuesen_US
dc.typeArticleen_US
dc.identifier.journalANALYTICAL AND BIOANALYTICAL CHEMISTRYen_US
dc.citation.volume404en_US
dc.citation.issue5en_US
dc.citation.epage1287en_US
dc.contributor.department資訊工程學系zh_TW
dc.contributor.departmentDepartment of Computer Scienceen_US
dc.identifier.wosnumberWOS:000307957800003-
dc.citation.woscount4-
Appears in Collections:Articles


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