標題: Application of 2-Azido-2-deoxythioglycosides for beta-Glycoside Formation and Oligosaccharide Synthesis
作者: Mong, Kwok-Kong Tony
Yen, Yu-Fang
Hung, Wei-Cheng
Lai, Yen-Hsun
Chen, Jiun-Han
應用化學系
Department of Applied Chemistry
關鍵字: Azides;Carbohydrates;Glycosylation;Glycopeptides;Regioselectivity
公開日期: 1-五月-2012
摘要: Most natural 2-acetamido-2-deoxyglycosides exist in a 1,2-trans-beta-glycosidic configuration. This study investigated the use of 2-azido-2-deoxythioglycosides for 1,2-trans-beta-glycosidic bond formation under low-concentration glycosylation conditions. Further application of the 2-azido-2-deoxythioglycosyl substrates for one-pot oligosaccharide synthesis was demonstrated in the synthesis of protected beta-(1?6)-N-acetylglucosamine trimer, core-6serine conjugate, and F1a serine conjugate.
URI: http://hdl.handle.net/11536/16334
ISSN: 1434-193X
期刊: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume: 
Issue: 15
結束頁: 3009
顯示於類別:期刊論文


文件中的檔案:

  1. 000303994100014.pdf