標題: Acyl and Silyl Group Effects in Reactivity-Based One-Pot Glycosylation: Synthesis of Embryonic Stem Cell Surface Carbohydrates Lc(4) and IV(2)Fuc-Lc(4)
作者: Hsu, Yun
Lu, Xin-An
Zulueta, Medel Manuel L.
Tsai, Chih-Ming
Lin, Kuo-I
Hung, Shang-Cheng
Wong, Chi-Huey
應用化學系
Department of Applied Chemistry
公開日期: 14-三月-2012
摘要: Relative reactivity evaluations showed the graded arming of toluenyl thioglucosides by variously positioned silyl groups but not by their acyl counterparts. These findings were applied in reactivity-based one-pot assembly of linker-attached Lc(4) and IV(2)Fuc-Lc(4), which are components of human embryonic stem cell surface. The sugar-galectin-1 binding was also examined.
URI: http://dx.doi.org/10.1021/ja300284x
http://hdl.handle.net/11536/15802
ISSN: 0002-7863
DOI: 10.1021/ja300284x
期刊: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume: 134
Issue: 10
起始頁: 4549
結束頁: 4552
顯示於類別:期刊論文


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