Title: Chemical Synthesis of the Englerins
Authors: Pouwer, Rebecca H.
Richard, Jean-Alexandre
Tseng, Chih-Chung
Chen, David Y. -K.
Department of Applied Chemistry
Keywords: cancer;guaianolide;natural products;sesquiterpene;total synthesis
Issue Date: 2-Jan-2012
Abstract: In the long lasting battle against cancer, Nature sometimes gives a helping hand to researchers to find new drugs for the treatment of diseases and improvement of patients' well-being. Englerin A has emerged as a promising anticancer candidate as well as being an exciting synthetic challenge for organic chemists. This focus review summarizes the total syntheses reported to date and the synthetic approaches toward analogues of this fascinating natural product.
URI: http://dx.doi.org/10.1002/asia.201100780
ISSN: 1861-4728
DOI: 10.1002/asia.201100780
Volume: 7
Issue: 1
Begin Page: 22
End Page: 35
Appears in Collections:Articles

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