|標題:||Chemical Synthesis of the Englerins|
|作者:||Pouwer, Rebecca H.|
Chen, David Y. -K.
Department of Applied Chemistry
|關鍵字:||cancer;guaianolide;natural products;sesquiterpene;total synthesis|
|摘要:||In the long lasting battle against cancer, Nature sometimes gives a helping hand to researchers to find new drugs for the treatment of diseases and improvement of patients' well-being. Englerin A has emerged as a promising anticancer candidate as well as being an exciting synthetic challenge for organic chemists. This focus review summarizes the total syntheses reported to date and the synthetic approaches toward analogues of this fascinating natural product.|
|期刊:||CHEMISTRY-AN ASIAN JOURNAL|