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dc.contributor.authorLee, Chia-Yien_US
dc.contributor.authorLiu, Chin-Hsingen_US
dc.contributor.authorChen, Hung-Chien_US
dc.contributor.authorSun, Chi-Chinen_US
dc.contributor.authorYao, Yen-Poen_US
dc.contributor.authorChao, Shih-Chunen_US
dc.date.accessioned2019-08-02T02:15:34Z-
dc.date.available2019-08-02T02:15:34Z-
dc.date.issued2019-01-01en_US
dc.identifier.issn0030-3747en_US
dc.identifier.urihttp://dx.doi.org/10.1159/000499695en_US
dc.identifier.urihttp://hdl.handle.net/11536/152237-
dc.description.abstractObjectives: Evaluate the correlation between basal macular circulation and late structural damage in progressed high-tension glaucoma (HTG) and normal-tension glaucoma (NTG) via optical coherence tomography angiography (OCTA). Methods: Patients who received an OCTA examination were divided into progressed HTG, progressed NTG, and well-controlled HTG (control) groups. Superficial macular vessel density (SmVD), deep macular vessel density (DmVD), foveal avascular zone (FAZ), and flow area of the outer retina and choriocapillaris were obtained by one OCTA device. Associations between macular angiography and glaucoma parameters, including the visual field, retinal nerve fiber layer, and ganglion cell complex, were analyzed. Results: A total of 60 eyes from 60 patients were enrolled. The progressed HTG and NTG groups had lower SmVD than the control group, while the progressed NTG group had lower DmVD and a larger FAZ than the control group. The flow area of the outer retina in the progressed HTG group was lower than that of the control. A significant correlation between SmVD and glaucoma parameters was found in the progressed HTG group, while a similar correlation between SmVD and DmVD to glaucoma parameters was observed in the progressed NTG group. Conclusion: The progressed HTG and NTG patients showed an impaired vascular intake before significant disease development compared to well-controlled cases.en_US
dc.language.isoen_USen_US
dc.subjectGlaucomaen_US
dc.subjectNormal-tension glaucomaen_US
dc.subjectOptical coherence tomography angiographyen_US
dc.subjectMaculaen_US
dc.subjectVessel densityen_US
dc.subjectRetinal nerve fiber layeren_US
dc.subjectGanglion cell complexen_US
dc.titleCorrelation between Basal Macular Circulation and Following Glaucomatous Damage in Progressed High-Tension and Normal-Tension Glaucomaen_US
dc.typeArticleen_US
dc.identifier.doi10.1159/000499695en_US
dc.identifier.journalOPHTHALMIC RESEARCHen_US
dc.citation.volume62en_US
dc.citation.issue1en_US
dc.citation.spage46en_US
dc.citation.epage54en_US
dc.contributor.department電機工程學系zh_TW
dc.contributor.departmentDepartment of Electrical and Computer Engineeringen_US
dc.identifier.wosnumberWOS:000473614500005en_US
dc.citation.woscount0en_US
Appears in Collections:Articles