標題: Multi-Target Many-Reactant Sample Preparation for Reactant Minimization on Microfluidic Biochips
作者: Lei, Yung-Chun
Lin, Tien-Kuo
Huang, Juinn-Dar
電子工程學系及電子研究所
Department of Electronics Engineering and Institute of Electronics
關鍵字: Sample preparation;microfluidic biochips;reactant minimization
公開日期: 1-Jan-2018
摘要: Sample preparation is one of essential steps in biochemical applications. It produces solutions with target concentrations through mixing various reactants in a specific way. In this paper, we propose a reactant cost minimization technique, M2SPA, for multi-target many-reactant sample preparation on microfluidic biochips through maximally sharing identical intermediate solutions among different targets. M2SPA first represents target concentrations as a recipe cube, searches all feasible candidates for intermediate solution sharing among targets, and then selects the one with the best cost saving for action. Experimental results show that the proposed algorithm can reduce up to 15.7% of reactant cost as compared to a state-of-the-art method.
URI: http://dx.doi.org/10.1109/ISVLSI.2018.00124
http://hdl.handle.net/11536/150727
ISSN: 2159-3469
DOI: 10.1109/ISVLSI.2018.00124
期刊: 2018 IEEE COMPUTER SOCIETY ANNUAL SYMPOSIUM ON VLSI (ISVLSI)
起始頁: 655
結束頁: 659
Appears in Collections:Conferences Paper