標題: Additional Vitamin and Mineral Support for Patients with Severe Burns: A Nationwide Experience from a Catastrophic Color-Dust Explosion Event in Taiwan
作者: Chen, Li-Ru
Yang, Bing-Shiang
Chang, Chih-Ning
Yu, Chia-Meng
Chen, Kuo-Hu
機械工程學系
Department of Mechanical Engineering
關鍵字: vitamin;mineral;burns;nutritional support
公開日期: 1-Nov-2018
摘要: Major burn injuries, which encompass >= 20% of the total body surface area (TBSA), are the most severe form of trauma because of the stress response they provoke, which includes hypermetabolism, muscle wasting, and stress-induced diabetes. In 2015, a color-dust explosion disaster occurred in the Formosa Fun Coast of Taiwan and injured 499 people, who were transferred via a nationwide emergency delivery system. Some recommendations are currently available regarding vitamin and mineral support for wound healing and recovery in severe burns, but there is a lack of evidence to confirm the benefits. Thus, the current study aimed to investigate the effects of additional vitamin and mineral support for patients with severe burn injuries. Sixty-one hospitalized individuals with major burns (full thickness and >= 20% TBSA) were classified into the supplement (n = 30) and control (n = 31) groups, according to whether they received supplementation with additional vitamins, calcium, and magnesium. There were significant differences between the supplement and control groups in the incidence of wound infection (30.0% vs. 77.4%, p < 0.001), sepsis (13.3% vs. 41.9%, p = 0.021), and hospitalization days (51.80 vs. 76.81, p = 0.025). After adjustment, logistic regression analysis revealed that, compared to those in the control group, patients in the supplement group had a lower risk for wound infection (OR 0.11; 95% CI 0.03-0.43; p = 0.002) and sepsis (OR 0.09; 95% CI 0.01-0.61; p = 0.014). Supplementation of multiple vitamins, calcium, and magnesium reduced the risk of wound infection and sepsis, shortened the time of hospitalization, and can be considered for use in major burns.
URI: http://dx.doi.org/10.3390/nu10111782
http://hdl.handle.net/11536/148524
ISSN: 2072-6643
DOI: 10.3390/nu10111782
期刊: NUTRIENTS
Volume: 10
Appears in Collections:Articles


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