標題: Fabrication of silicon dioxide nano array for bio-mimicking of molecular interactions
作者: Lu, Hui-Hsin
Lin, Chii-Wann
Hsiao, Tzu-Chien
Lee, Chih-Kung
Hsu, Su-Ming
資訊工程學系
Department of Computer Science
關鍵字: electrochemical atomic force microscopy;nano biochip;silicon dioxide nanopattems
公開日期: 1-Jan-2008
摘要: We employed atomic force microscopy (AFM) with bias control to fabricate oxided nanopatterns on silicon surface with feature size down to 50nm. The relationship of silicon dioxide nanopattems against humidity was studied and then the optimal parameter was used to make oxide nanoarry for interaction of biotin and streptavidin. The scanning function of AFM was utilized to verify the different height of biomolecules. According to our experimental results, using nano biochip of silicon dioxide can decrease the monitoring scale to nanometer and can be the nano-platform for monitoring the behavior of biomolecular interaction. We anticipate mimicking the correlation of single molecular behavior and an array of biomolecular behavior to understand the coincidence of them.
URI: http://dx.doi.org/10.1117/12.762919
http://hdl.handle.net/11536/146833
ISBN: 978-0-8194-7040-9
ISSN: 0277-786X
DOI: 10.1117/12.762919
期刊: NANOSCALE IMAGING, SENSING, AND ACTUATION FOR BIOMEDICAL APPLICATIONS V
Volume: 6865
起始頁: 0
結束頁: 0
Appears in Collections:Conferences Paper


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