|標題:||Investigation of nanoparticle-assisted ultrasound therapy for treating implanted breast tumors in mice|
Chen, Nelson G.
Institute of Molecular Medicine and Bioengineering
|關鍵字:||ultrasound;cancer;nanoparticle-assisted ultrasound therapy;ultrasound-nanoparticle interactions|
|摘要:||The presence of nanoparticles within an ultrasonic field has been previously shown to cause ultrasound to preferentially destroy cancerous cells over corresponding normal cells. Such treatment, termed nanoparticle-assisted ultrasound therapy (NAUT), has now been applied to subcutaneously implanted tumors in mice. Xenografted tumors were exposed to therapeutic ultrasound, with and without intratumoral injections of nanoparticles over a period of 4 weeks. Post-treatment, tumors that received nanoparticle injections were found to be substantially smaller than controls, suggesting that nanoparticle presence significantly increases the efficacy of ultrasonic treatment of solid tumors.|
|期刊:||2017 IEEE 17TH INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (IEEE-NANO)|
|Appears in Collections:||Conferences Paper|