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dc.contributor.authorChua, Chian Semen_US
dc.contributor.authorHuang, Shih-Yien_US
dc.contributor.authorCheng, Chiao-Wenen_US
dc.contributor.authorBai, Chyi-Hueyen_US
dc.contributor.authorHsu, Chien-Yehen_US
dc.contributor.authorChiu, Hung-Wenen_US
dc.contributor.authorHsu, Jung-Lungen_US
dc.date.accessioned2019-04-03T06:41:27Z-
dc.date.available2019-04-03T06:41:27Z-
dc.date.issued2017-12-01en_US
dc.identifier.issn0025-7974en_US
dc.identifier.urihttp://dx.doi.org/10.1097/MD.0000000000009094en_US
dc.identifier.urihttp://hdl.handle.net/11536/144380-
dc.description.abstractAbdominal pain is one of the key symptoms of irritable bowel syndrome (IBS). Studies have indicated an increase in the incidence of IBS in Asia. However, yet the pathophysiology of this disease remains unknown. Women are more likely to develop the condition than men, especially the constipation-predominant type. Essential fatty acid (EFA) malnutrition is one of several theories discussing the mechanism of IBS. The authors hypothesized that significant EFA deficiency may cause abdominal pain in patients with IBS. However, because patterns in the oral intake of EFAs differ between cultures, the authors narrowed this study to examine the nutritional status of Asian female patients with IBS The authors investigated Asian female patients with IBS and compared them with a group of healthy controls. Thirty patients with IBS and 39 healthy individuals were included in this study. The participants' age, height, weight, and waist size were recorded. The 24-item Hamilton Depression Rating Scale was documented. Both erythrocyte and plasma fatty acid content were analyzed through gas-liquid chromatography. The authors found that patients with IBS exhibited significantly higher scores for depression, higher proportions of plasma saturated fatty acids and monounsaturated fatty acids, and lower proportions of docosahexaenoic acid and total omega-3 polyunsaturated fatty acids in plasma are associated with IBS in Asian female patients. Further study is indicated to confirm the causality of this association.en_US
dc.language.isoen_USen_US
dc.subjectdocosahexaenoic aciden_US
dc.subjecteicosapentaenoic aciden_US
dc.subjectessential fatty aciden_US
dc.subjectirritable bowel syndromeen_US
dc.titleFatty acid components in Asian female patients with irritable bowel syndromeen_US
dc.typeArticleen_US
dc.identifier.doi10.1097/MD.0000000000009094en_US
dc.identifier.journalMEDICINEen_US
dc.citation.volume96en_US
dc.citation.issue49en_US
dc.citation.spage0en_US
dc.citation.epage0en_US
dc.contributor.department運輸與物流管理系 註:原交通所+運管所zh_TW
dc.contributor.departmentDepartment of Transportation and Logistics Managementen_US
dc.identifier.wosnumberWOS:000422799500123en_US
dc.citation.woscount0en_US
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