標題: LED Induced Autofluorescence (LIAF) Imager with eight multi-filters for Oral Cancer Diagnosis
作者: Huang, Ting-Wei
Cheng, Nai-Lun
Tsai, Ming-Hsui
Chiou, Jin-Chern
Mang, Ou-Yang
分子醫學與生物工程研究所
電機工程學系
Institute of Molecular Medicine and Bioengineering
Department of Electrical and Computer Engineering
關鍵字: Autofluorescence;filter;oral cancer;LED;induced
公開日期: 1-Jan-2016
摘要: Oral cancer is one of the serious and growing problem in many developing and developed countries. The simple oral visual screening by clinician can reduce 37,000 oral cancer deaths annually worldwide. However, the conventional oral examination with the visual inspection and the palpation of oral lesions is not an objective and reliable approach for oral cancer diagnosis, and it may cause the delayed hospital treatment for the patients of oral cancer or leads to the oral cancer out of control in the late stage. Therefore, a device for oral cancer detection are developed for early diagnosis and treatment. A portable LED Induced autofluorescence (LIAF) imager is developed by our group. It contained the multiple wavelength of LED excitation light and the rotary filter ring of eight channels to capture ex-vivo oral tissue autofluorescence images. The advantages of LIAF imager compared to other devices for oral cancer diagnosis are that LIAF imager has a probe of L shape for fixing the object distance, protecting the effect of ambient light, and observing the blind spot in the deep port between the gumsgingiva and the lining of the mouth. Besides, the multiple excitation of LED light source can induce multiple autofluorescence, and LIAF imager with the rotary filter ring of eight channels can detect the spectral images of multiple narrow bands. The prototype of a portable LIAF imager is applied in the clinical trials for some cases in Taiwan, and the images of the clinical trial with the specific excitation show the significant differences between normal tissue and oral tissue under these cases.
URI: http://dx.doi.org/10.1117/12.2212836
http://hdl.handle.net/11536/136446
ISBN: 978-1-62841-934-4
ISSN: 0277-786X
DOI: 10.1117/12.2212836
期刊: DESIGN AND QUALITY FOR BIOMEDICAL TECHNOLOGIES IX
Volume: 9700
起始頁: 0
結束頁: 0
Appears in Collections:Conferences Paper


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