Title: Bovine serum albumin detection and quantitation based on capacitance measurements of liquid crystals
Authors: Lin, Chi-Hao
Lee, Mon-Juan
Lee, Wei
Institute of Imaging and Biomedical Photonics
Issue Date: 29-Aug-2016
Abstract: Liquid crystal (LC)-based biosensing is generally limited by the lack of accurate quantitative strategies. This study exploits the unique electric capacitance properties of LCs to establish quantitative assay methods for bovine serum albumin (BSA) biomolecules. By measuring the voltage-dependent electric capacitance of LCs under an alternating-current field with increasing amplitude, positive correlations were derived between the BSA concentration and the electric capacitance parameters of LCs. This study demonstrates that quantitative analysis can be achieved in LC-based biosensing through electric capacitance measurements extensively employed in LCD research and development. Published by AIP Publishing.
URI: http://dx.doi.org/10.1063/1.4962169
ISSN: 0003-6951
DOI: 10.1063/1.4962169
Volume: 109
Issue: 9
Appears in Collections:Articles