標題: Impact of baseline characteristics on outcomes of carotid artery stenting in acute ischemic stroke patients
作者: Yu, Cheng-Sheng
Lin, Chih-Ming
Liu, Chi-Kuang
Lu, Henry Horng-Shing
生物科技學院
統計學研究所
大數據研究中心
College of Biological Science and Technology
Institute of Statistics
Big Data Res Ctr
關鍵字: carotid artery stenting;modified Rankin Scale;ischemic stroke;finite-state machine;resistance index
公開日期: 1-Jan-2016
摘要: Carotid artery stenting is an effective treatment for ischemic stroke patients with moderate-to-severe carotid artery stenosis. However, the midterm outcome for patients undergoing this procedure varies considerably with baseline characteristics. To determine the impact of baseline characteristics on outcomes following carotid artery stenting, data from 107 eligible patients with a first episode of ischemic stroke were collected by retrospective chart review. A modified Rankin Scale (mRS) was used to divide patients into two baseline groups, mRS <= 2 and mRS >2. A three-step decision-tree statistical analysis was conducted. After weighting the decision-tree parameters, the following impact hierarchy was obtained: admission low-density lipoprotein, gouty arthritis, chronic kidney disease, ipsilateral common carotid artery resistance index, contralateral ophthalmic artery resistance index, sex, and dyslipidemia. The finite-state machine model demonstrated that, in patients with baseline mRS <= 2, 46% had an improved mRS score at follow-up, whereas 54% had a stable mRS score. In patients with baseline mRS > 2, a stable mRS score was observed in 75%, improved score in 23%, and a poorer score in 2%. Admission low-density lipoprotein was the strongest predictive factor influencing poststenting outcome. In addition, our study provides further evidence that carotid artery stenting can be of benefit in first-time ischemic stroke patients with baseline mRS scores > 2.
URI: http://dx.doi.org/10.2147/TCRM.S104933
http://hdl.handle.net/11536/133561
ISSN: 1178-203X
DOI: 10.2147/TCRM.S104933
期刊: THERAPEUTICS AND CLINICAL RISK MANAGEMENT
Volume: 12
起始頁: 495
結束頁: 504
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