標題: Eliminating the interference of ascorbic acid and uric acid to the amperometric glucose biosensor by cation exchangers membrane and size exclusion membrane
作者: Yuan, CJ
Hsu, CL
Wang, SC
Chang, KS
生物科技學系
Department of Biological Science and Technology
關鍵字: PVA-SbQ;nafion;planar electrode;amperometric biosensor;polyion
公開日期: 1-Dec-2005
摘要: The characteristics of a multiuse planar amperometric biosensor modified with Nafion and/or polyion membrane were investigated. A new enzyme immobilization process was proposed, in which the polyvinyl alcohol bearing a styrylpyridinium (SbQ)/glucose oxidase composite was treated with glutaraldehyde vapor prior to the photo-crosslinking reaction. The resulting planar enzyme electrode remains active for at least 150 days. Compared with poly-L-lysine/poly (4-stryenesulfonate) polyion complex membrane the Nafion membrane showed marked effect to reduce the electrochemical response of the modified planar enzyme electrode to the biological interferents, such as ascorbic acid and uric acid. Furthermore, Nafion membrane can effective restricting the oxidized anionic interferent to adhear on its surface, thereby the fouling of the electrode was avoided.
URI: http://dx.doi.org/10.1002/elan.200503359
http://hdl.handle.net/11536/13015
ISSN: 1040-0397
DOI: 10.1002/elan.200503359
期刊: ELECTROANALYSIS
Volume: 17
Issue: 24
起始頁: 2239
結束頁: 2245
Appears in Collections:Articles


Files in This Item:

  1. 000234420600006.pdf