Feasibility and Penetration depth study for Sterilization of Porcine Cancellous Bone using Atmospheric-Pressure Argon Plasma Jets
This study aims to investigate the feasibility of the application and penetration depth of non-thermal atmosphere pressure argon plasma jet （APPJ） on the bone sterilization in orthopedic surgeries. Toward this end, a series of experiments including the plasma sterilization area on agar plate, the cell morphology observation, the feasibility as well as the penetration depth experiments were conducted. The plasma was generated by dielectric barrier discharge plasma jet. The cancellous bone samples were harvested from porcine vertebra while the bacterial strain was E.coli. The Taguchi method was incorporated to effectively improve the experiment efficiency by reducing test parameters. It was found that bacterial amount decreases with plasma treating time, which indicates the feasibility of plasma sterilization. Meanwhile bacterial amount was seen to increase with increasing depth. In addition, it can be concluded from experimental results that the treating time was the primary factor influencing the sterilization efficiency while the treating points as well as the treating distance were relatively secondary.
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