Title: A new pyrene-based aggregation induced ratiometric emission probe for selective detections of trivalent metal ions and its living cell application
Authors: Singh, Ashutosh
Singh, Ravinder
Shellaiah, Muthaiah
Prakash, Epperla Chandra
Chang, Huan-Cheng
Raghunath, Putikam
Lin, Ming-Chang
Lin, Hong-Cheu
Department of Materials Science and Engineering
Department of Applied Chemistry
Keywords: Pyrene-based sensor;Schiff base;Trivalent sensor;Aggregation induced ratiometric emission
Issue Date: 1-Feb-2015
Abstract: We synthesize a newly designed pyrene-based fluorescent probe FBP containing a Schiff base and amide linkage as a receptor, which demonstrates selective UV-vis and fluorometric detections of trivalent metal ions in various semi-aqueous solution conditions. Interestingly, by increasing water contents the aggregation induced ratiometric emissions (AIREs) of photoluminescence in FBP solutions (in DMSO/H2O) are enhanced from blue to green due to the excimer formation of the aggregates in water. In addition, the enhanced aggregated ratiometric green fluorescence behaviors of FBP in the presence of trivalent metal ions (Al3+, Fe3+, and Cr3+) are observed in semi-aqueous solutions as well as the solid state, which is well utilized to detect trivalent metal ions in living cells. Further verification of the probe detections, their interactions toward trivalent metal ions are well characterized by the time-resolved photoluminescence (TRPL) of spectroscopic responses as well as theoretical calculations. Therefore, we believe the application of such a new AIRE-based approach is first reported among Schiff base and pyrene-based fluorescentchemo- and bio-sensors. (C) 2014 Elsevier B.V. All rights reserved.
URI: http://dx.doi.org/10.1016/j.snb.2014.09.105
ISSN: 0925-4005
DOI: 10.1016/j.snb.2014.09.105
Volume: 207
Begin Page: 338
End Page: 345
Appears in Collections:Articles