標題: Fabrication of microfluidic devices using dry film photoresist for microchip capillary electrophoresis
作者: Tsai, YC
Jen, HP
Lin, KW
Hsieh, YZ
應用化學系
Department of Applied Chemistry
關鍵字: microchip capillary electrophoresis;amperometric detection;dry film photoresist;microfluidic devices
公開日期: 14-四月-2006
摘要: An inexpensive, disposable microfluidic device was fabricated from a dry film photoresist using a combination of photolithographic and hot roll lamination techniques. A microfluidic flow pattern was prefabricated in a dry film photoresist tape using traditional photolithographic methods. This tape became bonded to a poly(methyl methacrylate) (PMMA) sheet with prepouched holes when passed through a hot roll laminator. A copper working electrode and platinum decoupler was readily incorporated within this microchip. The integrated microchip device was then fixed in a laboratory-built Plexiglas holder prior to its use in microchip capillary electrophoresis. The performance of this device with amperometric detection for the separation of dopamine and catechol was examined. The separation was complete within 50 s at an applied potential of 200 V/cm. The relative standard deviations (RSD) of analyte migration times were less than 0.71%, and the theoretical plate numbers for dopamine and catechol were 3.2 x 10(4) and 4.1 x 10(4), respectively, based on a 65 min separation channel. (c) 2005 Elsevier B.V. All rights reserved.
URI: http://dx.doi.org/10.1016/j.chroma.2005.12.003
http://hdl.handle.net/11536/12381
ISSN: 0021-9673
DOI: 10.1016/j.chroma.2005.12.003
期刊: JOURNAL OF CHROMATOGRAPHY A
Volume: 1111
Issue: 2
起始頁: 267
結束頁: 271
顯示於類別:會議論文


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  1. 000236656300022.pdf